United flights to Panama from $ 312*

Discover Panama with flights to Panamá City.

Visit Panamá City

  • Explore Panamá Viejo historic district, a UNESCO World Heritage Site. Tour the ruins of the first European settlement on the Pacific Coast, hear tales of its destruction in 1671 at the hands of the Welsh buccaneer Henry Morgan and examine pre-Hispanic artifacts.
  • Hike through tropical forests at Parque Natural Metropolitano. Go to the mirador for breathtaking views of the city and the Miraflores Locks. See tití monkeys, sloths and iguanas, watch for over 250 bird species and stroll alongside the Río Curundú.
  • Learn about the Panama Canal’s construction at the Panama Canal Museum, including the political and historical context of this engineering feat.

Featured premium cabin flights to Panama

$

New York/Newark (EWR)to

Panama City (PTY)
02/21/25 - 02/23/25

Roundtrip

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Business

from
$ 1,482*
Viewed: 4 hours ago

Los Angeles (LAX)to

Panama City (PTY)
12/24/24 - 01/02/25

Roundtrip

|

Business

from
$ 1,957*
Viewed: 16 hours ago

San Francisco (SFO)to

Panama City (PTY)
02/04/25 - 02/26/25

Roundtrip

|

Business

from
$ 2,145*
Viewed: 25 minutes ago

Houston (IAH)to

Panama City (PTY)
03/12/25 - 03/20/25

Roundtrip

|

Business

from
$ 1,545*
Viewed: 2 hours ago

Miami (MIA)to

Panama City (PTY)
02/14/25 - 02/24/25

Roundtrip

|

Business

from
$ 2,473*
Viewed: 40 minutes ago

Denver (DEN)to

Panama City (PTY)
01/21/25 - 01/27/25

Roundtrip

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Business

from
$ 1,430*
Viewed: 11 hours ago

San Antonio (SAT)to

Panama City (PTY)
03/13/25 - 03/18/25

Roundtrip

|

Business

from
$ 1,187*
Viewed: 16 hours ago

Austin (AUS)to

Panama City (PTY)
01/22/25 - 02/05/25

Roundtrip

|

Business

from
$ 1,083*
Viewed: 6 hours ago

Orlando (MCO)to

Panama City (PTY)
03/07/25 - 03/12/25

Roundtrip

|

Business

from
$ 2,394*
Viewed: 6 hours ago

Dallas (DFW)to

Panama City (PTY)
12/29/24 - 01/06/25

Roundtrip

|

Business

from
$ 1,380*
Viewed: 3 hours ago

Chicago (ORD)to

Panama City (PTY)
12/24/24 - 12/27/24

Roundtrip

|

Business

from
$ 1,462*
Viewed: 3 hours ago

San Diego (SAN)to

Panama City (PTY)
03/12/25 - 03/21/25

Roundtrip

|

Business

from
$ 1,742*
Viewed: 1 hour ago

Phoenix (PHX)to

Panama City (PTY)
12/30/24 - 01/13/25

Roundtrip

|

Business

from
$ 1,134*
Viewed: 4 hours ago

Washington, D.C. (IAD)to

Panama City (PTY)
01/11/25 - 01/20/25

Roundtrip

|

Business

from
$ 1,422*
Viewed: 6 hours ago

Seattle (SEA)to

Panama City (PTY)
01/20/25 - 01/23/25

Roundtrip

|

Business

from
$ 1,502*
Viewed: 3 hours ago

Boston (BOS)to

Panama City (PTY)
01/01/25 - 01/05/25

Roundtrip

|

Business

from
$ 2,568*
Viewed: 8 hours ago

Washington, D.C. (DCA)to

Panama City (PTY)
03/13/25 - 03/17/25

Roundtrip

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Business

from
$ 978*
Viewed: 5 hours ago

Fort Lauderdale (FLL)to

Panama City (PTY)
01/31/25 - 02/02/25

Roundtrip

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Business

from
$ 2,402*
Viewed: 8 hours ago

Philadelphia (PHL)to

Panama City (PTY)
12/24/24 - 12/29/24

Roundtrip

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Business

from
$ 1,333*
Viewed: 10 hours ago

Cleveland (CLE)to

Panama City (PTY)
01/22/25 - 01/26/25

Roundtrip

|

Business

from
$ 1,409*
Viewed: 6 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply.