United flights to Panama from US *

Discover Panama with flights to Panamá City.

Visit Panamá City

  • Explore Panamá Viejo historic district, a UNESCO World Heritage Site. Tour the ruins of the first European settlement on the Pacific Coast, hear tales of its destruction in 1671 at the hands of the Welsh buccaneer Henry Morgan and examine pre-Hispanic artifacts.
  • Hike through tropical forests at Parque Natural Metropolitano. Go to the mirador for breathtaking views of the city and the Miraflores Locks. See tití monkeys, sloths and iguanas, watch for over 250 bird species and stroll alongside the Río Curundú.
  • Learn about the Panama Canal’s construction at the Panama Canal Museum, including the political and historical context of this engineering feat.

Featured premium cabin flights to Panama

US $

Mexico City (MEX)to

Panama City (PTY)
11/02/2025 - 22/02/2025

Roundtrip

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Business

from
US $ 2,968*
Viewed: 45 minutes ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply.

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